Efficacy of topical Phenol and Menthol combination in chronic pruritic Mustard gas induced skin lesions
نویسندگان
چکیده مقاله:
Background and aim: Chronic skin lesions are common late complications of sulfur mustard intoxication which would result in numerous complaints including pruritus, skin dryness and burn feeling. In chemical warfare injured veterans, pruritus is the most common complaint in chronic status with significant effects on patient's quality of life. This study has evaluated efficacy of topical phenol 1% and menthol 1% combination in treatment of pruritus in chemical warfare injured veterans in comparison with placebo.Materials and Methods: This randomized double blind clinical trial was done on chemical warfare injured veterans with mustard gas induced pruritus. Eighty patients were randomly divided to 2 equal groups, one group treated with phenol 1% and menthol 1% combination and other group with placebo for 6 weeks and the therapeutic effects were evaluated according to pruritus scores.Results: Pruritus score was significantly reduced in active group compared to placebo group (P=0.026).Conclusion: Phenol 1% and menthol 1% combination has significant therapeutic effect for mustard gas induced pruritus in chemical warfare injured veterans.
منابع مشابه
Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure.
INTRODUCTION Chronic skin lesions are common late complications of sulphur mustard exposure in veterans injured in chemical warfare. Pruritus is the most common complaint in the chronic phase, with significant effects on the patient's quality of life. The current study evaluated the efficacy of a combination of one percent phenol and one percent menthol in the control of pruritus in these affec...
متن کاملComparison of Skin Erythema and Melanin Level in Sulfur Mustard Induced Chronic Skin Lesions and Normal Skin
Background: Sulfur mustard gas is a chemical agent that has been used in many wars, especially in Iran-Iraq war. This chemical agent affects many organs including lungs, eyes and skin, causing numerous acute and chronic lesions including erythema and hyperpigmentation, respectively. This study was conducted to evaluate erythema and melanin in subjects with a history of exposure to sulfur ...
متن کاملSkin lesions in 800 Iranian victims of Mustard gas, 14-20 years after exposure
Background: Mustard gas is a disabling chemical weapon and was widely used in first world war and Iraq-Iran war. Its toxic effects could be acute or chronic and they could particularly affects lungs, eyes and skin. Objective: To study the frequency of chronic complications of sulfure Mustard gas in Iranian victims 14 to 20 years after exposure. Patients and Methods: This descriptive cross-secti...
متن کاملClinical Efficacy of Topical Avena sativa Versus Betamethasone in Chronic Pruritus due to Sulfur Mustard Exposure
Background: Avena sativa, a well-known herbal medicine; has been used in various skin diseases such as eczema, burn and pruritus. Objective: The objective of this study was to evaluate the effect of this herbal medicine for treatment of chronic pruritus in Sulfur Mustard (SM) exposed patients. Methods: Veterans who referred to Baghiat-Allah dermatologic clinic for itching problems were examin...
متن کاملTopical Cyclosporine A for Mustard Gas Induced Ocular Surface Disorders
PURPOSE To evaluate the effectiveness of topical cyclosporine A 0.05% for treatment of mustard gas-induced ocular surface disorders with special attention to conjunctival goblet cell density in patients with severe dry eye. METHODS This prospective clinical study included 20 eyes of 20 patients previously exposed to mustard gas with dry eye syndrome unresponsive to artificial tears. Before an...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 9 شماره 2
صفحات 114- 121
تاریخ انتشار 2006-07-01
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023